Trifunctional purine biosynthetic protein adenosine-3

GART

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1MEJ, 1MEN, 1MEO, 1NJS, 1RBM, 1RBQ, 1RBY, 1RBZ, 1RC0, 1RC1, 1ZLX, 1ZLY, 2QK4, 2V9Y, 4EW1, 4EW2, 4EW3, 4ZZ2, 4ZZ3, 4ZZ1, 4ZYV, 4ZZ0, 4ZYY, 4ZYX, 4ZYZ, 4ZYT, 4ZYU, 4ZYW

Identifiers

Aliases

GART, AIRS, GARS, GARTF, PAIS, PGFT, PRGS, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

External IDs

OMIM: 138440 MGI: 95654 HomoloGene: 637 GeneCards: GART

Gene ontology
Molecular function	• transferase activity • nucleotide binding • phosphoribosylglycinamide formyltransferase activity • metal ion binding • ligase activity • catalytic activity • hydroxymethyl-, formyl- and related transferase activity • ATP binding • phosphoribosylformylglycinamidine cyclo-ligase activity • phosphoribosylamine-glycine ligase activity
Cellular component	• cytoplasm • cytosol • extracellular exosome
Biological process	• purine nucleotide biosynthetic process • glycine metabolic process • 'de novo' IMP biosynthetic process • brainstem development • biosynthetic process • response to organic substance • cerebellum development • ribonucleoside monophosphate biosynthetic process • tetrahydrofolate biosynthetic process • response to inorganic substance • purine ribonucleoside monophosphate biosynthetic process • cerebral cortex development • metabolic process • purine nucleobase biosynthetic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


2618


14450

Ensembl


n/a


ENSMUSG00000022962

UniProt


P22102


Q64737

RefSeq (mRNA)


NM_000819 NM_001136005 NM_001136006 NM_175085


NM_010256

RefSeq (protein)


NP_000810 NP_001129477 NP_001129478 NP_780294


NP_034386.2 NP_034386

Location (UCSC)

Chr 21: 33.5 – 33.54 Mb

Chr 16: 91.62 – 91.65 Mb

PubMed search

1MEJ, 1MEN, 1MEO, 1NJS, 1RBM, 1RBQ, 1RBY, 1RBZ, 1RC0, 1RC1, 1ZLX, 1ZLY, 2QK4, 2V9Y, 4EW1, 4EW2, 4EW3, 4ZZ2, 4ZZ3, 4ZZ1, 4ZYV, 4ZZ0, 4ZYY, 4ZYX, 4ZYZ, 4ZYT, 4ZYU, 4ZYW

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