Tyrone is an unincorporated community in Texas County, Missouri, in the United States. The community consists of several houses.
A post office called Tyrone was established in 1891, and remained in operation until 1962. The community was named after Tyrone, Pennsylvania, the native home of a first settler.
On February 27, 2015, Tyrone was the scene of a mass murder, carried out by Joseph Jesse Aldridge. He killed seven people and wounded another person before taking his own life.
Coordinates: 37°12′12″N 91°52′36″W / 37.20333°N 91.87667°W