UPAR

PLAUR

Protein PLAUR PDB 1YWH.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1YWH, 2FD6, 3BT1, 3BT2, 3U73, 3U74, 2I9B, 4K24, 4QTI

Identifiers

PLAUR, CD87, U-PAR, UPAR, URKR, plasminogen activator, urokinase receptor

External IDs

OMIM: 173391 MGI: 97612 HomoloGene: 48120 GeneCards: PLAUR

Gene ontology
Molecular function	• protein domain specific binding • protein binding • urokinase plasminogen activator receptor activity • enzyme binding • receptor binding • receptor activity
Cellular component	• integral component of membrane • cell projection • endoplasmic reticulum lumen • endoplasmic reticulum membrane • membrane • focal adhesion • invadopodium membrane • integral component of plasma membrane • extracellular region • cell junction • anchored component of membrane • extracellular exosome • extrinsic component of membrane • plasma membrane • specific granule membrane • cell surface
Biological process	• movement of cell or subcellular component • positive regulation of protein phosphorylation • negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway • fibrinolysis • negative regulation of intrinsic apoptotic signaling pathway • urokinase plasminogen activator signaling pathway • negative regulation of apoptotic process • blood coagulation • attachment of GPI anchor to protein • chemotaxis • positive regulation of release of cytochrome c from mitochondria • positive regulation of DNA binding • positive regulation of epidermal growth factor receptor signaling pathway • regulation of proteolysis • signal transduction • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE PLAUR 210845 s at fs.png

PBB GE PLAUR 211924 s at fs.png

PBB GE PLAUR 214866 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5329


18793


ENSG00000011422


ENSMUSG00000046223


Q03405


P35456

RefSeq (mRNA)


NM_001005376 NM_001005377 NM_001301037 NM_002659


NM_011113

RefSeq (protein)


NP_001005376 NP_001005377 NP_001287966 NP_002650


NP_035243

Location (UCSC)

Chr 19: 43.65 – 43.67 Mb

Chr 7: 24.46 – 24.48 Mb

PubMed search

1YWH, 2FD6, 3BT1, 3BT2, 3U73, 3U74, 2I9B, 4K24, 4QTI

ENSG00000011422

ENSMUSG00000046223

NM_001005376
NM_001005377
NM_001301037
NM_002659

NP_001005376
NP_001005377
NP_001287966
NP_002650

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Wikipedia

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