Von Meyenburg complex

A bile duct hamartoma or biliary hamartoma, is a benign tumour-like malformation of the liver.

They are classically associated with polycystic liver disease, as may be seen in the context of polycystic kidney disease, and represent a malformation of the liver plate.

The eponymous terms (von Meyenburg complex, Meyenburg complex) are named for Hanns von Meyenburg.

At CT scans, bile duct hamartomas appear as small, well-defined hypo- or isoattenuating masses with little or no enhancement after contrast administration. At MRI, they appear hypointense on T1-weighted images, iso- or slightly hyperintense on T2-weighted images, and hypointense after administration of gadolinium based contrast-agent. On imaging, multiple hamartomas may look similar to metastases or microabscesses.

Micrograph of a bile duct hamartoma. Trichrome stain.

Low magnification micrograph of a bile duct hamartoma. Trichrome stain.

Gross pathologic appearance of a large bile duct hamartoma.

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