Wayne is a rural unincorporated community in Republic County, Kansas, United States.
Wayne had its start in the year 1884 by the building of the railroad through that territory.
A post office was opened in Wayne in 1884, and remained in operation until it was discontinued in 1971.
Coordinates: 39°42′53″N 97°32′31″W / 39.71472°N 97.54194°W