| State Trunk Highway 121 | ||||
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| Route information | ||||
| Maintained by WisDOT | ||||
| Length: | 45.07 mi (72.53 km) | |||
| Major junctions | ||||
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| East end: |
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| Location | ||||
| Counties: | Buffalo, Trempealeau, Jackson | |||
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State Trunk Highway 121 (often called Highway 121, STH 121 or WIS 121) is a state highway in the U.S. state of Wisconsin. It runs in east–west in west-central Wisconsin from Gilmanton to Alma Center.