The 2011 season was Santos Futebol Clube's ninety-ninth season in existence and the club's fifty-second consecutive season in the top flight of Brazilian football.

On 8 November 2010, Santos announced Adílson Batista to coach the team and his debut was on January in the Campeonato Paulista. But, on 27 February 2011, Santos sacked him although he had only one defeat in 11 matches.Marcelo Martelotte assumed as caretaker until 5 April when Muricy Ramalho was officially announced as new coach.

On 15 May, Santos won their 19th Campeonato Paulista title beating their rival Corinthians 2–1 on aggregate in the final. Santos also won their 3rd Copa Libertadores title, beating Uruguay's Peñarol 2–1 on aggregate after the first leg had ended scoreless in Montevideo. As they won the Copa Libertadores, they played the 2011 FIFA Club World Cup but lost 4–0 in the final to Spanish's Barcelona.

Last updated: 18 December 2011
Source: Match reports in competitive matches
Ordered by start team
0 shown as blank

YS= Youth system player with first team experience.

Last updated: 18 December 2011
Source: Campeonato Paulista, Campeonato Brasileiro, Copa Libertadores
Ordered by , and
= Number of bookings; = Number of sending offs after a second yellow card; = Number of sending offs by a direct red card.

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