2016 San Luis Open Challenger Tour – Singles
| Singles | |
|---|---|
| 2016 San Luis Open Challenger Tour | |
| Champions |
 Peđa Krstin
|
| Runners-up |
 Marcelo Arévalo
|
| Final score | 6–4, 6–2 |
Guido Pella was the defending champion, but chose not to defend his title.
Peđa Krstin won the title, defeating Marcelo Arévalo 6–4, 6–2 in the final.
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