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Names | |
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IUPAC name
3-(4-hydroxyphenyl)-2-oxo-propanoic acid
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Other names
4-Hydroxyphenylpyruvate
p-Hydroxyphenylpyruvic acid p-Hydroxyphenylpyruvate |
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Identifiers | |
156-39-8 ![]() |
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3D model (Jmol) | Interactive image |
ChEBI |
CHEBI:15999 ![]() |
ChEMBL |
ChEMBL607712 ![]() |
ChemSpider |
954 ![]() |
DrugBank |
DB07718 ![]() |
ECHA InfoCard | 100.005.322 |
6629 | |
KEGG |
C01179 ![]() |
PubChem | 979 |
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Properties | |
C9H8O4 | |
Molar mass | 180.157 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
4-Hydroxyphenylpyruvic acid (4-HPPA) is an intermediate in the metabolism of the amino acid phenylalanine. The aromatic side chain of phenylalanine is hydroxylated by the enzyme phenylalanine hydroxylase to form tyrosine. The conversion from tyrosine to 4-HPPA is in turn catalyzed by tyrosine aminotransferase. Additionally, 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment.
It is an intermediary compound in the biosynthesis of scytonemin.