| Names | |
|---|---|
|
IUPAC name
3-(4-hydroxyphenyl)-2-oxo-propanoic acid
|
|
| Other names
4-Hydroxyphenylpyruvate
p-Hydroxyphenylpyruvic acid p-Hydroxyphenylpyruvate |
|
| Identifiers | |
|
156-39-8 |
|
| 3D model (Jmol) | Interactive image |
| ChEBI |
CHEBI:15999 |
| ChEMBL |
ChEMBL607712 |
| ChemSpider |
954 |
| DrugBank |
DB07718 |
| ECHA InfoCard | 100.005.322 |
| 6629 | |
| KEGG |
C01179 |
| PubChem | 979 |
|
|
|
|
| Properties | |
| C9H8O4 | |
| Molar mass | 180.157 g/mol |
|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
|
|
|
|
| Infobox references | |
4-Hydroxyphenylpyruvic acid (4-HPPA) is an intermediate in the metabolism of the amino acid phenylalanine. The aromatic side chain of phenylalanine is hydroxylated by the enzyme phenylalanine hydroxylase to form tyrosine. The conversion from tyrosine to 4-HPPA is in turn catalyzed by tyrosine aminotransferase. Additionally, 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment.
It is an intermediary compound in the biosynthesis of scytonemin.