HTATSF1

HTATSF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DIT
Identifiers
Aliases	HTATSF1, TAT-SF1, TATSF1, dJ196E23.2, HIV-1 Tat specific factor 1
External IDs	MGI: 1919709 HomoloGene: 40950 GeneCards: HTATSF1
Gene ontology Molecular function • nucleic acid binding • RNA binding Cellular component • U2-type spliceosomal complex • nucleus • U2 snRNP • nucleoplasm Biological process • regulation of transcription from RNA polymerase II promoter • viral genome replication • regulation of DNA-templated transcription, elongation • regulation of transcription, DNA-templated • transcription, DNA-templated • mRNA splicing, via spliceosome Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27336	72459
Ensembl	ENSG00000102241	ENSMUSG00000067873
UniProt	O43719	Q8BGC0
RefSeq (mRNA)	NM_001163280 NM_014500	NM_028242 NM_029371
RefSeq (protein)	NP_001156752 NP_055315	NP_082518 NP_083647
Location (UCSC)	Chr X: 136.5 – 136.51 Mb	Chr X: 57.05 – 57.07 Mb
PubMed search

2DIT

27336

72459

ENSG00000102241

ENSMUSG00000067873

O43719

Q8BGC0

NM_001163280
NM_014500

NM_028242
NM_029371

NP_001156752
NP_055315

NP_082518
NP_083647

HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene.

Whereas most DNA sequence-specific transcription factors increase the rate of initiation and interact with enhancer or promoter DNA, human immunodeficiency virus-1 (HIV-1) Tat predominantly stimulates elongation and interacts with the trans-acting responsive (TAR) RNA element. Tat is essential for HIV replication.[supplied by OMIM]

HTATSF1 has been shown to interact with SUPT5H and GTF2F2.

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Wikipedia