South Carolina Highway 421
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| Augusta Road | ||||
| Route information | ||||
| Maintained by SCDOT | ||||
| Length: | 10.36 mi (16.67 km) | |||
| Existed: | 1952 – present | |||
| Major junctions | ||||
| South end: |
    US 1 / US 78 / US 278 / SC 125 in Clearwater
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| North end: |
US 1 / US 78 in Aiken
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| Location | ||||
| Counties: | Aiken | |||
| Highway system | ||||
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South Carolina Highway 421 (SC 421) is a primary state highway in the U.S. state of South Carolina. It is an alternate route to US 1/US 78 between Aiken and Augusta, Georgia.
SC 421 begins where it splits off from the US 1/US 78 (Jefferson Davis Highway) west of North Augusta; it immediately connecting with US 278/SC 125 (Atomic Road). Heading northeast, it parallels US 1/US 78 to its south, going through the towns of Clearwater, Burnettown, Langley, Gloverville and Warrenville. Upon entering Aiken, it reconnects with US 1/US 78. Majority of the highway is four-lanes that travels a total of 10.5 miles (16.9 km).
Established by 1952 as a renumbering of US 1/US 78, which was realigned onto new four-lane routing just north of it. The route has remained unchanged since inception.
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