KRT83

KRT83
Identifiers
Aliases	KRT83, HB3, Hb-3, KRTHB3, keratin 83
External IDs	MGI: 3690448 HomoloGene: 68248 GeneCards: KRT83
Gene ontology Molecular function • protein binding • structural molecule activity Cellular component • keratin filament • intermediate filament • extracellular space • cytosol Biological process • hair cycle • aging • epidermis development • keratinization • cornification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3889	100126226
Ensembl	ENSG00000170523	ENSMUSG00000067613
UniProt	P78385	E9Q1Y9
RefSeq (mRNA)	NM_002282	NM_001201323
RefSeq (protein)	NP_002273	NP_001188252
Location (UCSC)	Chr 12: 52.31 – 52.32 Mb	Chr 15: 101.49 – 101.49 Mb
PubMed search

3889

100126226

ENSG00000170523

ENSMUSG00000067613

P78385

E9Q1Y9

NM_002282

NM_001201323

NP_002273

NP_001188252

Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1 (KRT81), KRTHB3 (KRT83, this protein), and KRTHB6 (KRT86), is highly related. The other less-related subfamily includes KRTHB2 (KRT82), KRTHB4 (KRT84), and KRTHB5 (KRT85). All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.

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Wikipedia